Barr body a blob of
Barr body a blob of condensed chromatin visible at the edge of the nucleus in some interphase cells of females that represents the inactive X chromosome.
The Lyon hypothesis that gene dosage imbalance between males and females, because of the presence of two X chromosomes in females (XX) as opposed to only one in males (XY), is compensated for by random inactivation of one of the X chromosomes in the somatic cells of females.
Dosage compensation any system that equalizes the amount of product produced by genes present in different numbers.
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Heredity and Variation
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12th science biology
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A Barr body (named after discoverer Murray Barr) is the inactive X chromosome in a female somatic cell, rendered inactive in a process called lyonization, in those species in which sex is determined by the presence of the Y (including humans) or W chromosome rather than the diploidy of the X or Z. The Lyon hypothesis states that in cells with multiple X chromosomes, all but one are inactivated during mammalian embryogenesis. This happens early in embryonic development at random in mammals, except in marsupials and in some extra-embryonic tissues of some placental mammals, in which the father's X chromosome is always deactivated.